Mastocytic Enterocolitis Associated Food Intolerance Missed Due to Lack of Special Stains of Intestinal Biopsies and Celiac Gene Testing?
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Submitted by The Food Doc Journal
Increased mast cells have been reported in association with eosinophils in the gut in patients with celiac disease and inflammatory bowel diseases like ulcerative colitis and Crohn’s disease condition. Mastocytic enterocolitis (entero=small bowel, colitis- colon + -itis= inflammation) is a newly recognized disorder defined specifically by the microscopic presence of increased mast cells (>20 mast cells/high power field) in the gut, typically associated with abdominal pain and diarrhea diagnosed as IBS-D.
